Molecular group:
Adhesion molecules
Molecule/Cell:
CD54 (ICAM-1)
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
ICAM-1-/-
Lethal infection (Con):
N.I.
Lethal infection (EG):
N.I.
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
↓ platelet rolling and adhesion in brain microvasculature
Refs:
Sun et al., 2003, Infect Immun
Hyperlink: