Molecular group:
Adhesion molecules
Molecule/Cell:
CD54 (ICAM-1)
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
5 x 10^4
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
ICAM-1-/-
Lethal infection (Con):
N.I.
Lethal infection (EG):
N.I.
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
% pRBCs alveolar capillaries = % pRBCs in large blood vessels of lung (in contrast to WT)
Refs:
Piguet et al., 2001, Am J Pathol
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