Molecular group:
Adhesion molecules
Molecule/Cell:
CD40L
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
5 x 10^4
Mouse genetic background (Con):
C57BL/6J
Experimental treatment group (EG):
anti-CD40L
Lethal infection (Con):
N.I.
Lethal infection (EG):
N.I.
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
↓ thrombocytopenia and ↓ microparticles in plasma
Refs:
Piguet et al., 2002, Apoptosis
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