CD36

Molecular group: 
Adhesion molecules
Molecule/Cell: 
CD36
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6 x 129/Sv
Level of backcrossing: 
Backcrossed for 4 generations
Experimental treatment group (EG): 
CD36 -/- chimeras
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (100%)
Pathology (EG): 
CM (75%)
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
25 % of CD36 -/- chimeras expressing only CD36 in hematopoietic cells had a prolonged survival (2-3 weeks) without neurological symptoms
Refs: 
Cunha-Rodrigues et al., 2007, Malar J