CXCR3

Molecular group: 
Chemokines and receptors
Molecule/Cell: 
CXCR3
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
2 x 10^6
Mouse genetic background (Con): 
C57BL/6
Experimental treatment group (EG): 
in vitro activated WT and CXCR3 -/- effector CD8+ T cells (day 5)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM
Pathology (EG): 
CM
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
Similar number of WT and CXCR3 -/- cells in spleen and ↓ number of CXCR3 -/- cells in brain after competitive (co)transfer in WT mice
Refs: 
Campanella et al., 2008, Proc Natl Acad Sci U S A