Molecular group:
Chemokines and receptors
Molecule/Cell:
CXCR3
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
CXCR3 -/-
Level of backcrossing:
Backcrossed for 11 generations
Experimental treatment group (EG):
adoptive transfer of in vivo activated WT splenocytes or CD8+ T cells (day 0)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (100%)
Pathology (EG):
CM (70%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Miu et al., 2008, J Immunol
Hyperlink: