Molecular group:
Chemokines and receptors
Molecule/Cell:
CCR5
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
CCR5 -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (100%)
Pathology (EG):
CM (100%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
CM was delayed for 1 day
Refs:
Nitcheu et al., 2003, J Immunol
Hyperlink: