Molecular group:
Chemokines and receptors
Molecule/Cell:
CXCL10 (IP-10)
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
2 x 10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
Backcrossed for 9 generations
Experimental treatment group (EG):
CXCL10 -/-
Lethal infection (Con):
90% (at the end of observation day 20)
Lethal infection (EG):
40% (at the end of observation day 20)
Pathology (Con):
CM (90%)
Pathology (EG):
CM (40%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Campanella et al., 2008, Proc Natl Acad Sci U S A
Hyperlink: