CXCL10 (IP-10)

Molecular group: 
Chemokines and receptors
Molecule/Cell: 
CXCL10 (IP-10)
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
2 x 10^6
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
Backcrossed for 9 generations
Experimental treatment group (EG): 
CXCL10 -/-
Lethal infection (Con): 
90% (at the end of observation day 20)
Lethal infection (EG): 
40% (at the end of observation day 20)
Pathology (Con): 
CM (90%)
Pathology (EG): 
CM (40%)
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
N.I.
Refs: 
Campanella et al., 2008, Proc Natl Acad Sci U S A