TGF-b

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
TGF-b
Plasmodium strain: 
Plasmodium chabaudi chabaudi AS
pRBC infection titer: 
5 x 10^4
Mouse genetic background (Con): 
BALB/c Cr Slc
Experimental treatment group (EG): 
anti-TGF-b
Lethal infection (Con): 
yes
Lethal infection (EG): 
20%
Pathology (Con): 
N.I.
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Slightly lower peak and spontaneous decline
Additional phenotypes (EG vs Con): 
↑ serum IFN-g (day 7) and NO (day 10)
Refs: 
Tsutsui et al., 1999, Infect Immun