Molecular group:
Cytokines and receptors
Molecule/Cell:
LIGHT
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^4
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
LIGHT -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (100%)
Pathology (EG):
CM (100%)
Parasitemia (EG vs Con):
Decreased
Additional phenotypes (EG vs Con):
Similar neurologic symptoms
Refs:
Randall et al., 2008, J Immunol
Hyperlink: