LTb

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
LTb
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6J
Level of backcrossing: 
Backcrossed for at least 10 generations
Experimental treatment group (EG): 
LTb -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (100%)
Pathology (EG): 
CM (70%)
Parasitemia (EG vs Con): 
Increased
Additional phenotypes (EG vs Con): 
Neurological symptoms were delayed (days); ↓ CD54+CD8+ and CD69+CD8+ T cells in brain; anemia
Refs: 
Togbe et al., 2008, PLoS One