Molecular group:
Cytokines and receptors
Molecule/Cell:
TNFR2
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
TNFR2 -/-
Lethal infection (Con):
N.I.
Lethal infection (EG):
N.I.
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
ICAM-1 increased on d4 and similar on d6 in brain; increased on d4-6 in lungs
Refs:
Bauer et al., 2002, Microcirculation
Hyperlink: