Molecular group:
Cytokines and receptors
Molecule/Cell:
TNF-a
Plasmodium strain:
Plasmodium chabaudi adami 556KA
pRBC infection titer:
10^5 or 10^6
Mouse genetic background (Con):
CBA/CaH
Experimental treatment group (EG):
rHu-TNF-a
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Delayed onset and decreased peak
Additional phenotypes (EG vs Con):
N.I.
Refs:
Clark et al., 1987, J Immunol
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