Molecular group:
Cytokines and receptors
Molecule/Cell:
TNF-a
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
anti-TNF-a (PAb)
Lethal infection (Con):
no
Lethal infection (EG):
50%
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Slightly delayed onset (1 day)
Additional phenotypes (EG vs Con):
N.I.
Refs:
Jacobs et al., 1996, Infect Immun
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