Molecular group:
Cytokines and receptors
Molecule/Cell:
TNF-a
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
N.I.
Level of backcrossing:
N.I.
Experimental treatment group (EG):
TNF-a -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM
Pathology (EG):
CM
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
Similar indoleamine 2,3-dioxygenase-1 mRNA expression in the brain
Refs:
Hansen et al., 2004, Int J Parasitol
Hyperlink: