Molecular group:
Cytokines and receptors
Molecule/Cell:
IFN-g
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
IFN-g -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (96,5%)
Pathology (EG):
No CM
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
No ↑ brain IDO activity
Refs:
Sanni et al., 1998, Am J Pathol
Hyperlink: