IFN-g

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
IFN-g
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
IFN-g -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (96,5%)
Pathology (EG): 
No CM
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
No ↑ brain IDO activity
Refs: 
Sanni et al., 1998, Am J Pathol