Molecular group:
Cytokines and receptors
Molecule/Cell:
IFN-g/CTLA-4
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^5
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
IFN-g -/- + anti-CTLA-4
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
No CM
Pathology (EG):
No CM
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Jacobs et al., 2002, J Immunol
Hyperlink: