Molecular group:
Cytokines and receptors
Molecule/Cell:
IFNabR
Plasmodium strain:
Plasmodium chabaudi AS
pRBC infection titer:
10^5
Mouse genetic background (Con):
129 Sv/Ev
Level of backcrossing:
N.I.
Experimental treatment group (EG):
IFNabR -/-
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Increased weight loss and hypothermia
Refs:
Voisine et al., 2010, Int J Parasitol
Hyperlink: