Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-18
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^4
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
rIL-18
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
Prolonged survival (~ 2 weeks)
Refs:
Singh et al., 2002, J Immunol
Hyperlink: