Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-18
Plasmodium strain:
Plasmodium yoelii 17XNL
pRBC infection titer:
5 x 10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
Backcrossed for 5 generations
Experimental treatment group (EG):
IL-18 -/-
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Increased
Additional phenotypes (EG vs Con):
N.I.
Refs:
Cramer et al., 2008, Microbes Infect
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