Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-17
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
5 x 10^4
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
IL-17-/- (17KO)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (80%)
Pathology (EG):
CM (80%)
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Similar neurological symptoms
Refs:
Ishida et al., 2010, Biochem Biophys Res Commun
Hyperlink: