IL-17

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
IL-17
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
5 x 10^4
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
IL-17-/- (17KO)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (80%)
Pathology (EG): 
CM (80%)
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
Similar neurological symptoms
Refs: 
Ishida et al., 2010, Biochem Biophys Res Commun