Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-12/IFN-g
Plasmodium strain:
Plasmodium berghei XAT
pRBC infection titer:
10^4
Mouse genetic background (Con):
CBA/JNCrj
Experimental treatment group (EG):
rIL-12 + anti-IFN-g
Lethal infection (Con):
no
Lethal infection (EG):
yes
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Increased and no clearance
Additional phenotypes (EG vs Con):
N.I.
Refs:
Yoshimoto et al., 1998, J Infect Dis
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