Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-10
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
BALB/c
Experimental treatment group (EG):
anti-IL-10
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
HP&A
Pathology (EG):
HP&A
Parasitemia (EG vs Con):
similar
Additional phenotypes (EG vs Con):
Similar mortality; ↑ TNF-a
Refs:
Kossodo et al., 1997, Immunology
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