Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-10
Plasmodium strain:
Plasmodium yoelii 17XNL
pRBC infection titer:
10^6
Mouse genetic background (Con):
129/Ola x C57BL/6 (WT = 129/Ola)
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
IL-10 -/-
Lethal infection (Con):
no
Lethal infection (EG):
not in 30 days
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
N.I.
Refs:
Van der heyde et al., 1997, Exp Parasitol
Hyperlink: