Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-6
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
10^4
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
rIL-6
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Decreased second peak and earlier clearance
Additional phenotypes (EG vs Con):
↑ parasite-specific IgG1, IgG2a and IgG2b and similar IgG3 serum levels
Refs:
Akanmori et al., 1996, Parasite Immunol
Hyperlink: