IL-6

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
IL-6
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
CBA/Ca
Experimental treatment group (EG): 
anti-IL-6
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (80%)
Pathology (EG): 
CM (80%)
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
Similar IgM and ↓ IgG
Refs: 
Grau et al., 1990, J Exp Med