Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-4
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
10^6
Mouse genetic background (Con):
A/J
Experimental treatment group (EG):
anti-IL-4
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Similar iNOS mRNA expression in spleen 7 days p.i.. similar NO3- levels in serum 7 days p.i.; similar spleen weight 7 days p.i.
Refs:
Jacobs et al. 1996, Infect Immun
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