Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-4
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
129 x C57BL/6
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
IL-4 -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (89%)
Pathology (EG):
CM (44,5%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Yañez et al., 1996, J Immunol
Hyperlink: