Molecular group:
Ig against self protein Ag
Molecule/Cell:
IgG against total brain protein extract
Plasmodium strain:
Plasmodium falciparum
Organ:
Plasma
Population:
India
Transmission:
Unstable
Adult/Pediatric:
Pediatric and adult
Patient number:
98
Additional differences:
Malaria (CM + SM + UM) > HC; median number of cerebral antigens recognized by plasma IgG: malaria (CM + SM + UM) > HC; reactivity to brain antigens (factor 1 score): CM > SM = UM > HC; similar profile reactivity to brain antigens for Gabonese children (67) and Indian patients, but with different predominant activity (Gabonese predominantly recognize spectrin, Indians beta tubulin 3); + correlation with TNF-a, TGF-b, IL-10 and IL-1b
Refs:
Bansal et al., 2009, PLoS One
Hyperlink: