Parasite-spec IgG4

Molecular group: 
Ig subfamilies and receptors
Molecule/Cell: 
Parasite-spec IgG4
Plasmodium strain: 
Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae
Organ: 
Serum
Population: 
Brazil
Transmission: 
Unstable
Adult/Pediatric: 
Adult
SM/NCSM vs UM: 
Patient number: 
233
Additional differences: 
NCSM > AM; prevalence of IgG4: NCSM = UM = AM; interactions with IgE: NCSM > UM, AM; - correlation with the number of previous clinical malaria attacks; significantly ↑ levels for patients undergoing their 1 clinical malaria attack; no change in avidity index with number of previous clinical malaria attacks
Refs: 
Leoratti et al., 2008, Malar J