Parasite-spec IgG3

Molecular group: 
Ig subfamilies and receptors
Molecule/Cell: 
Parasite-spec IgG3
Plasmodium strain: 
Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae
Organ: 
Serum
Population: 
Brazil
Transmission: 
Unstable
Adult/Pediatric: 
Adult
SM/NCSM vs UM: 
Patient number: 
233
Additional differences: 
NCSM < AM; prevalence of IgG3: NCSM < UM, AM; interactions with IgG1 and IgG2: NCSM < UM, AM; + correlation with the number of previous clinical malaria attacks; significantly ↑ levels for patients with > 5 previous clinical malaria attacks compared to patients with 0 – 5 previous clinical malaria attacks; no change in avidity index with number of previous clinical malaria attacks
Refs: 
Leoratti et al., 2008, Malar J