Molecular group:
Ig subfamilies and receptors
Molecule/Cell:
Parasite-spec IgG1
Plasmodium strain:
Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae
Organ:
Serum
Population:
Brazil
Transmission:
Unstable
Adult/Pediatric:
Adult
SM/NCSM vs UM:
<
Patient number:
233
Additional differences:
NCSM < AM; avidity index: NCSM < AM, UM; prevalence of IgG1: NCSM < UM, AM; predominance of high-avidity IgG1 in UM and AM, and low-avidity IgG1 in NCSM; IgG1 Ab frequency: P. falciparum > P. vivax and P. falciparum+P. vivax > P. vivax; interactions with IgG2 and IgG3: NCSM < UM, AM; + correlation with the number of previous clinical malaria attacks; significantly ↑ levels for patients with > 5 previous clinical malaria attacks compared to patients with 0 – 5 previous clinical malaria attacks; mean avidity index ↑ with number of previous clinical malaria attacks
Refs:
Leoratti et al., 2008, Malar J
Hyperlink: