Molecular group:
Ig subfamilies and receptors
Molecule/Cell:
Total IgE
Plasmodium strain:
Plasmodium falciparum
Organ:
Plasma
Population:
India
Transmission:
Stable
Adult/Pediatric:
Adult
SM/NCSM vs UM:
=
UM vs HC:
>
Patient number:
98
Additional differences:
NCSM > HC; ex-CM = CM = HC; endemic HC > non-endemic HC; IgE Indian adults > IgE Gabonese children; a ↑ % of patients with clinical disease had ↑ IgE levels than HC; no ↓ in IgE levels 30 days after treatment; + correlation with parasite load (UM and NCSM), plasma IFN-g, TNF-a and IL-10; ↑ expression of FceRI on mast cells after incubation with serum samples from patients from all groups; % of patients with functional P. falciparum IgE was slightly ↑ in HC and UM compared to CM and NCSM
Refs:
Duarte et al., 2007, Malar J
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