Molecular group:
Ig subfamilies and receptors
Molecule/Cell:
Total IgE
Plasmodium strain:
Plasmodium falciparum
Organ:
Plasma
Population:
Gabon
Transmission:
Stable
Adult/Pediatric:
Pediatric
CM vs NCSM:
=
CM vs UM:
=
SM/NCSM vs UM:
=
UM vs HC:
=
Patient number:
135
Additional differences:
HC = AM; a ↑ % of patients with clinical disease had ↑ IgE levels than HC and AM; no ↓ in IgE levels 30 days after treatment; + correlation with age, parasite load (UM) and plasma IL-10 (UM); - correlation with parasite load (AM, CM and NCSM) and plasma IL-10 (AM); ↑ expression of FceRI on mast cells after incubation with serum samples from patients from all groups; % of patients with functional P. falciparum IgE was ↑ in AM and UM compared to CM, NCSM and HC
Refs:
Duarte et al., 2007, Malar J
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