Total IgE

Molecular group: 
Ig subfamilies and receptors
Molecule/Cell: 
Total IgE
Plasmodium strain: 
Plasmodium falciparum
Organ: 
Serum
Population: 
Sudan, Ethiopia
Transmission: 
Unstable
Adult/Pediatric: 
Pediatric and adult
CM vs UM: 
SM/NCSM vs UM: 
Patient number: 
15
Additional differences: 
IgE-containing sera induced more TNF release when added to anti-IgE-coated plates (but not anti-IgG-coated plates) together with PBMC compared to control sera, and this was abrogated by IgE-depletion; IgG-anti-IgE-exposed PBMC showed ↑ staining of CD23 after 2-5 days of incubation
Refs: 
Perlmann et al., 1997, Infect Immun