TNF-a

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
TNF-a
Plasmodium strain: 
N.I.
Organ: 
Brain (PM)-IHC
Population: 
Malawi
Transmission: 
Stable
Adult/Pediatric: 
Pediatric (Adult)
CM vs NM-CNS: 
=
CM vs NM-NCNS: 
Patient number: 
14
Additional differences: 
TNF-a mRNA present in all CM cases, no TNF-a mRNA in NM-CNS, and in only 1 NM-NCNS case whereas TNF-a protein staining was found in all CM and NM-CNS brains but not in NM-NCNS brains; expressed by splenic MF from CM patients; + correlation with TGF-b and IL-1b
Refs: 
Brown et al., 1999, J Infect Dis