TNF-a

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
TNF-a
Plasmodium strain: 
Plasmodium falciparum
Organ: 
Plasma
Population: 
The Gambia
Transmission: 
Stable
Adult/Pediatric: 
Pediatric
SM† vs SM: 
Patient number: 
115
Additional differences: 
Levels did not significantly change during the first 24h; logistic regression indicated TNF-a levels > 300 pg/mL as an independently predictive of fatal outcome; + correlation with admission venous lactate concentrations, and blood IL-1a; - correlation with blood glucose concentration (not independently of hyperlactatemia)
Refs: 
Krishna et al., 1994, Trans R Soc Trop Med Hyg