Molecular group:
Leucocyte effector mechanisms and proteases
Molecule/Cell:
LMP7
Plasmodium strain:
Plasmodium yoelii 17NL
pRBC infection titer:
2,5 x 10^4
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
LMP7 -/-
Lethal infection (Con):
No
Lethal infection (EG):
No
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Decreased peak and faster clearance
Additional phenotypes (EG vs Con):
N.I.
Refs:
Duan et al., 2013, PLoS One
Hyperlink: