Isg15

Molecular group: 
Signal transduction and intracellular danger sensors
Molecule/Cell: 
Isg15
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
Isg15 -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (100%)
Pathology (EG): 
CM (100%)
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
N.I.
Refs: 
Berghout et al., 2013, PLoS Pathog