Molecular group:
Cytokines and receptors
Molecule/Cell:
IL-12p40
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6
Level of backcrossing:
N.I.
Experimental treatment group (EG):
IL-12p40 -/-
Lethal infection (Con):
yes
Lethal infection (EG):
~85% (at the end of observation day 20)
Pathology (Con):
CM (100%)
Pathology (EG):
CM (~85% at the end of observation day 20)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Berghout et al., 2013, PLoS Pathog
Hyperlink: