Molecular group:
Acute-phase proteins
Molecule/Cell:
CRP
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
5 x 10^5
Mouse genetic background (Con):
C57BL/6J
Level of backcrossing:
Backcrossed for more than 10 generations
Experimental treatment group (EG):
CRP-tg
Lethal infection (Con):
yes
Lethal infection (EG):
N.I.
Pathology (Con):
CM (100%)
Pathology (EG):
No CM
Parasitemia (EG vs Con):
Decreased
Additional phenotypes (EG vs Con):
N.I.
Refs:
Aggrey et al., 2013, J Immunol
Hyperlink: