CD11a/CD18 (LFA-1)

Molecular group: 
Adhesion molecules
Molecule/Cell: 
CD11a/CD18 (LFA-1)
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
5 x 10^5
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
LFA1 -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (100%)
Pathology (EG): 
CM (20%)
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
N.I.
Refs: 
Ramos et al., 2012, Parasite Immunol